Immune-inflammatory responses in the elderly: an update

The Emerging Role of Adipose Tissue-derived Leptin in Inflammatory and Immune Responses in Obesity: an Update

Leptin, an adipocyte-secreted peptide, has a dual role acting as hormone in central regulation of metabolism and energy homeostasis, and as cytokine to regulate the innate and adaptive immune response in normal and pathological conditions. This review provides a synopsis of recent advances regarding the emerging role of leptin as a modulator of inflammatory and immune responses in adipose tissu...

Liver diseases in the elderly: an update.

Although there are no liver diseases specific to advanced age, the clinical course and management of liver diseases in the elderly may differ in several aspects from those of younger adults. During the last decade an explosion of new knowledge in liver disease has provoked increasing enthusiasm among hepatologists. On the other hand, the development of new emerging conditions (e.g. non-alcoholi...

Inflammatory and Immune Responses in Depression

With high global chronic disease burden [1] and prevalence [2], mental illness is presently facing an enormous drug development challenge. In stark contrast to revolutionary, mostly serendipitous, discovery of psychiatric drugs between the end of 1940's and late 1950's, followed by a period of stagnancy during the next half a century, the last decade has witnessed drug development pipeline for ...

Update on Secretory Pathways in Plant Immune Responses Secretory Pathways in Plant Immune Responses

Innate immune receptors in plants detect the presence of microbial pathogens and trigger defense responses to terminate or restrict pathogen growth. The molecular mechanisms of receptor-mediated nonself recognition and subsequent intracellular signaling pathways have received much attention in the past. Less is known about the cellular mechanisms that contribute to the execution of immune respo...

hepatitis b immune globulin in liver transplantation prophylaxis: an update